Karen Cawston Bio, Research, Abstract http://www.ewu.edu/academics/trio-mcnair-scholar-program/past-and-present-participants/1996-research-interns/karen-cawston en-us Fri, 31 Oct 2014 10:44:00 UTC Fri, 31 Oct 2014 10:44:00 UTC webmaster@ewu.edu webmaster@ewu.edu

Karen Cawston

Bio, Research, AbstractKaren Cawston, McNair Scholar, Research, Nursing, Biology

1996 Research

Abstract: Documentation of Tentacle and Neural Regeneration of Two Land Slugs
Mentor: Stacia B. Moffett, PhD, WSU Department of Zoology


The neural regeneration of surgically removed tentacles of two land slugs, Arion ater and Limax maximus, was studied. Much documentation presently exists chronicling the regeneration ability of the gastropods. This ability for neural regeneration appears to be founded in gastropod evolutionary survival. Human neural regeneration occurs, but of a far more limited nature. In attempt to advance the understanding of human neural regeneration, the identification of the blood factors present during gastropod regeneration, as well as the sources and pathways involved, has been studied. To help document the presence of new neurons, bromodeoxyuridine (BrdU), which attaches to the nuclei of dividing cells, was injected into the animals. Primary and secondary antibodies were attached to the BrdU, with the secondary antibody having a fluorochrome marker conjugated to the antibody cells. This marker was visible under the fluorescent microscope. With such DNA marking, newly dividing cells, including neurons, become visible. To further document the process of neural regeneration, bioassay was also used. During cell growth, both stimulatory and inhibitory factors are present to control the growth process. The blood of the animals was added to mouse mammary cancer cells to identify either an inhibitory of stimulatory effect on the cancer cells. The bioassay further identifies characteristics of the molecules responsible for the effect and compares these to other molecules with similar attributes. The study of the regeneration of the nervous system of these animals is highly accessible, yet the chemical and molecular clues are shared with humans. Therefore, understanding how the process of neural regeneration occurs in the pulmonates enhances the study of nervous system regeneration in humans.

Programs by College/School EWU Home Admissions Apply for Admission Academics at Eastern Life at EWU Search Athletics http://blogs.ewu.edu Upcoming Events News Community Resources EWU on TwitterTemplate/ewulogo.png

Future Students

AdmissionsAdmissions InformationUndergraduate Admissions Graduate Studies International Admissions Apply for Admission Visit EWU Request InfoCosts and AcademicsCosts and Tuition Net Price Calculator Financial Aid & Scholarships Academic Overview Programs by College/School Off-Campus Degree ProgramsCampus LifeLife at EWU About EWU Housing & Residential Life Study Abroad Veterans Resource Center EWU Greek LifePlanning AheadAdmitted New Student Orientation Academic Calendar Bookstore Campus Map Information for Counselors

Current Students

http://access.ewu.edu/Students.xmlMost RequestedStudent Employment Programs by College/School Student Activities myEWU Portal Technology BookstoreStudent ServicesFinancial Aid and Scholarships Student Financial Services Health and Wellness Disability Support Services Counseling & Psychological Services Academic AdvisingAcademic ResourcesCatalog Academic Calendar Records and Registration Online Learning EagleNET CanvasCampus ServicesHousing & Residential Life Dining Services Recreation @ EWU EWU Libraries Parking Services Career Services

Faculty & Staff

StaffEmployee ResourcesHuman Resources Benefits Payroll Student Employment Academic Calendar Eastern 24/7ServicesParking University Police Mail Services Commute Trip Reduction Dining Services Marketing & CommunicationsAdministration & BusinessBusiness & Finance Budget Services Office of the President Office of the Provost Contract Services Facilities & PlanningTechnologyInformation Technology Help Desk EmailexternalClassroom Technology OIT Project Management NetStorage

Alumni & Friends

http://alumni.ewu.edu/Stay ConnectedAlumni Association Alumni Events Eastern Magazine Career Support Alumni Partnerships Office of AlumniSupport EWUGive Now EWU Foundation Ways to Give Philanthropic Impacts Eagle Athletic Association Planned GivingFriends of EWUBookstore Site Map Athletics Tickets Office EWU on Facebook Campus Recreation Visit EWUMost RequestedContinuing Education Events Photo Albums Alumni Gear Store EWU Events Calendar Alumni Search Give to EWU About EWU Site Map EWU Foundation Visit EWU Diversity EagleNET EWU Libraries Jobs Campus Locations Canvas AdministrationtrueHome ~ Academics ~ TRiO McNair Scholar Program ~ Past and Present Participants ~ 1996 Research Interns ~ Karen Cawston 2014 Research Interns 2013 Research Interns 2012 Research Interns 2011 Research Interns 2010 Research Interns 2009 Research Interns 2008 Research Interns 2007 Research Interns 2006 Research Interns 2005 Research Interns 2004 Research Interns 2003 Research Interns 2002 Research Interns 2001 Research Interns 2000 Research Interns 1999 Research Interns 1998 Research Interns 1997 Research Interns 1996 Research Interns
Academics at Eastern Ronald E. McNair Post Baccalaureate Achievement ProgramweeklyAcademics/TRiO-McNair-Scholar-Program/Continuing-and-Past-TRiO-McNair-Participants/1996-Research-Interns/Karen-Cawston.xmltruerssrssHTTP_ACCEPT:text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8 HTTP_ACCEPT_ENCODING:x-gzip, gzip, deflate HTTP_ACCEPT_LANGUAGE:en-us,en-gb,en;q=0.7,*;q=0.3 HTTP_HOST:www.ewu.edu HTTP_USER_AGENT:CCBot/2.0 (http://commoncrawl.org/faq/) Accept: text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8 Accept-Encoding: x-gzip, gzip, deflate Accept-Language: en-us,en-gb,en;q=0.7,*;q=0.3 Host: www.ewu.edu User-Agent: CCBot/2.0 (http://commoncrawl.org/faq/) http://www.ewu.edu/x9118.xmlhttp://www.ewu.edu/academics/trio-mcnair-scholar-program/past-and-present-participants/1996-research-interns/karen-cawston?rss=trueCCBot/2.0 (http://commoncrawl.org/faq/)