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Ronald E. McNair Post Baccalaureate Achievement ProgramWelcome to the Ronald E. McNair Post Baccalaureate Achievement Program
526 5th Street
Cheney, WA 99004
Dr. David Daberkow: Department of Biology, EWU
TRiO McNair Research Internship:____________________________________________________________
Pre-conditioning of Chronic Carbon Fiber Microelectrodes for Fast-Scan Cyclic Voltammetry
Dopamine is a neurotransmitter associated with reward-motivated behavior. Imbalances in the body have been associated to diseases such as Parkinson's, schizophrenia, and ADHD. Throughout the investigation of dopamine in the human brain, rodents have been used as disease models to track neurotransmitters such as dopamine.
With the use of rodent models, volammetry has been used to study dopamine release via current which can be converted into concentration of dopamine by means of calibration when flow cell is analyzed. Fast Scan Cyclic Voltammetry is a state-of-the-art method of monitoring dopamine signaling in the brain in real time. FSCV monitors dopamine signaling every 100 milliseconds. FSCV elicits dopamine current due to the application of differential potentials to the dopamine microelectrode surface. The oxidation and reduction of this process results in dopamine current flow at the carbon fiber microelectrode (CFM) surface.
Under the direction of Dr. David Daberkow, I am analyzing a specific pre-conditioning treatment impact on chronic silica encased carbon fiber microelectrodes used in dopamine monitoring in vivo.
Honors and Awards:______________________________________________________________________
- McNair Scholar Summer Internship, Awarded $2,800. The goal of the McNair Program is to increase the attainment of PhD degrees by students from underrepresented segments of society. (2014)